Dinis Toh^1,2, Lay Ping Tan^1,2, Divya Thirunavukarasu^1,2, Kowsalya Natarajan^1,2, Wira Bin Ambel^1,2 and Maurice HT Ling^2,3,4*

¹School of Health & Life Sciences, Teesside University, UK
²Management Development Institute of Singapore, Singapore
³Newcastle Australia Institute of Higher Education, University of Newcastle, Australia
⁴HOHY PTE LTD, Singapore

*Corresponding Author: Maurice HT Ling, Management Development Institute of Singapore, Singapore.

Received: April 13, 2026; Published: May 07, 2026

Abstract

Bacillus cereus is a bacterium with tolerance to diverse environmental stresses and demonstrated ability to enhance plant resilience to abiotic stressors, making it a promising candidate for soil conditioning, aquaculture probiotics, and metabolic engineering applications. Whole cell kinetic models are useful for in silico screening and evaluation of engineering approaches prior to experimental manipulations. However, there is no whole cell KM of B. cereus to date. Here, we present four simulatable whole cell KMs based on four strains of B. cereus; namely, (i) model bceDT26 for ATCC 14579 strain, (ii) model bczDT26 for E33L strain, (iii) model bcfKN26 for F837/76 strain, and (iv) model bcgLPT26 for G9842 strain. These models can be a baseline models for incorporating other cellular and growth processes, or as a system to examine cellular resource allocations necessary for engineering.

Keywords: Bacillus cereus; Whole-Cell Kinetic Model; Ordinary Differential Equations; AdvanceSyn Toolkit

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Citation

Citation: Maurice HT Ling., et al. “Four Ab Initio Whole Cell Kinetic Models of Bacillus cereus ATCC 14579 (bceDT26), E33L (bczDT26), F837/76 (bcfKN26) and G9842 (bcgLPT26)". Acta Scientific Microbiology 9.5 (2026): 33-39.

Copyright

Copyright: © 2026 Maurice HT Ling., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.