Supiana Dian Nurtjahyani¹*, Eko Susetyarini² and Ali Mustofa³

¹Postgraduate Universitas PGRI Ronggolawe, Tuban, Indonesia
²Departement of Biological Education, Faculty of Teaching and Education, Universitas Muhhamdiyah Malang, Indonesia
³Departement of Biological Education, Faculty of Teaching and Education, Universitas PGRI Ronggolawe, Tuban, Indonesia

*Corresponding Author: Supiana Dian Nurtjahyani, Postgraduate Universitas PGRI Ronggolawe, Tuban, Indonesia.

Received: February 11, 2025; Published: February 24, 2025

Abstract

Hepatitis C is an infectious disease transmitted through contaminated blood, including blood transfusions. The presence of anti-HCV antibodies in blood donors serves as a key indicator of hepatitis C virus (HCV) infection. This study analyzes the prevalence of anti-HCV in blood donors and evaluates associated risk factors. Using a retrospective approach, we examined serological screening results from a blood donor center over a specified period. The data was obtained through ELISA or similar serological methods used in donor screening. Among the total donors, 1.4% tested positive for anti-HCV. The prevalence varied based on age, gender, and donation history. Further analysis revealed that prior blood transfusions, non-sterile syringe use, and chronic liver disease significantly increased the risk of anti-HCV positivity (p < 0.05). Additionally, prevalence trends showed fluctuations over time, potentially linked to improved screening policies and shifting infection patterns. These findings highlight the ongoing importance of anti-HCV screening to ensure blood safety. Identifying risk factors can refine donor selection policies and enhance preventive strategies. Strengthening public health education, monitoring high-risk donors, and adopting more sensitive screening methods can help reduce HCV transmission through blood transfusions.

Keywords:Hepatitis C; Anti-HCV; Blood Donors; Prevalence; Risk Factors; Blood Screening

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Citation

Citation: Supiana Dian Nurtjahyani., et al. “Anti-HVC Detection Results in Blood Donors: Analysis of Prevalence and Risk Factors". Acta Scientific Microbiology 8.3 (2025): 66-68.

Copyright

Copyright: © 2025 Supiana Dian Nurtjahyani., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.