Acta Scientific Gastrointestinal Disorders (ASGIS)(ISSN: 2582-1091)

Research Article Volume 6 Issue 7

Current Trends in Intensive Therapy of Peritonitis and Abdominal Sepsis

Anatolii I Sukhodolia and Kostiantyn Yu Krenov*

National Pirogov Memorial Medical University, Bogomoletz Institute of Physiology of the National Academy of Medical Sciences of Ukraine, Khmelnytskyi Regional Hospital Municipal Non-Profit Enterprise of Khmelnytskyi Regional Council, Ukraine

*Corresponding Author: Kostiantyn Yu Krenov, National Pirogov Memorial Medical University, Bogomoletz Institute of Physiology of the National Academy of Medical Sciences of Ukraine, Khmelnytskyi Regional Hospital Municipal Non-Profit Enterprise of Khmelnytskyi Regional Council, Ukraine.

Received: May 15, 2023; Published: May 14, 2023


Introduction: Peritonitis is the most frequent complication of surgical emergencies of the abdominal organs and their injuries. This pathology is the cause of death in about 60% of cases of surgical emergencies. The course of this pathology depends on the nature and duration of the disease, the responsiveness of the macroorganism, and methods of treatment. Usually, several microorganisms act as an etiological factor. Urgent surgical treatment in order to eliminate the source of infection using the concept of damage control surgery, early adequate antibiotic therapy, the use of fluid resuscitation, inotropic and vasopressor support, efferent methods of therapy can minimize the development of complications and further progression of the disease with the implementation of the pattern of sepsis and septic shock, and save the lives of patients [32,33].

Materials and Methods: Literature sources of the PubMed database under the tags of ‘peritonitis’, ‘sepsis’, ‘destructive pancreatitis’ over the past 10 years were analysed.

Conclusion: Peritonitis and abdominal sepsis associated with its progression, despite the pluricausal structure of the pathology, require unified treatment approaches. Early sanitation of the pocket of infection, maintaining microcirculation at the proper level, the use of the principles of damage control surgery, and the early adequate prescription of antibiotic therapy with the creation of an appropriate concentration of drugs in the pocket is the key to success in the treatment of this category of patients.

 Keywords: Peritonitis; Abdominal Sepsis; Septic Shock; Resuscitation


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Citation: Anatolii I Sukhodolia and Kostiantyn Yu Krenov. “Current Trends in Intensive Therapy of Peritonitis and Abdominal Sepsis". Acta Scientific Gastrointestinal Disorders 6.7 (2023): 10-17.


Copyright: © 2023 Anatolii I Sukhodolia and Kostiantyn Yu Krenov. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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