Acta Scientific Gastrointestinal Disorders (ASGIS)(ISSN: 2582-1091)

Short Communication Volume 5 Issue 9

Surgical Care for Gastro-Intestinal Stromal Tumours

Patnala Mohan Patro*

Former Professor and HOD of Surgery, GIMSR, GITAM University, India

*Corresponding Author: Patnala Mohan Patro, Former Professor and HOD of Surgery, GIMSR, GITAM University, India.

Received: July 21, 2022; Published:

Gastrointestinal stromal tumors (GISTs) account for less than 1% of GI tumors, but they are the most common mesenchymal neoplasms of the GI tract [1]. GISTs are usually found in the stomach or small intestine but can occur anywhere along the GI tract and rarely have extra-GI involvement.


Surgery is the definitive therapy for localized GISTs [2]. Despite the proven success of Imatinib and other newer tyrosine kinase inhibitors, surgical resection remains the treatment of choice and offers the only chance for cure of GIST [3].


  1. PDQ Adult Treatment Editorial Board. “Gastrointestinal Stromal Tumors Treatment (Adult) (PDQ®)”. Health Professional Version (2020).
  2. Casli PG., et al. “ESMO Guidelines Committee, EURACAN and GENTURIS. Gastrointestinal stromal tumours: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up”. Annals of Oncology 1 (2022): 20-33.
  3. Guo Y., et al. “The Role of Surgical Resection Following Tyrosine Kinase Inhibitors Treatment in Patients with Advanced Gastrointestinal Stromal Tumors: A Systematic Review and Meta-analysis”.Journal of Cancer 23 (2019): 5785-5792.
  4. Katai H., et al. “Wedge resection of the stomach for gastric leiomyosarcoma”. British Journal of Surgery4 (1997): 560-561.
  5. National Comprehensive Cancer Network. “NCCN Clinical Practice Guidelines in Oncology: Gastrointestinal Stromal Tumors (GISTs)”. NCCN.
  6. Zhao Y., et al. “Retrospective Comparison of Endoscopic Full-Thickness Versus Laparoscopic or Surgical Resection of Small (≤ 5 cm) Gastric Gastrointestinal Stromal Tumors”. Journal of Gastrointestinal Surgery12 (2019): 2714-2721.
  7. Eisenberg BL and Judson I. “Surgery and imatinib in the management of GIST: emerging approaches to adjuvant and neoadjuvant therapy”.Annals of Surgical Oncology5 (2004): 465-475.
  8. Rutkowski P., et al. “Surgical treatment of patients with initially inoperable and/or metastatic gastrointestinal stromal tumors (GIST) during therapy with imatinib mesylate”. Journal of Surgical Oncology4 (2016): 304-311.
  9. Chen H., et al. “Complete hepatic resection of metastases from leiomyosarcoma prolongs survival”. Journal of Gastrointestinal Surgery 2 (1998): 151-155.


Citation: Patnala Mohan Patro. “Surgical Care for Gastro-Intestinal Stromal Tumours". Acta Scientific Gastrointestinal Disorders 5.9 (2022): .


Copyright: © 2022 Patnala Mohan Patro. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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