Hyperbaric Oxygen Therapy in Osteoradionecrosis of Jaw (ORNJ) Undergoing Radiation Therapy- A Perspective on Contemporary Understanding
Nanda Kishore Ghoshal
Consultant Prosthodontist, Kolkata, India
*Corresponding Author: Nanda Kishore Ghoshal, Consultant Prosthodontist, Kolkata, India.
Received:
September 30, 2025; Published: October 01, 2025
Abstract
Radiation therapy is a prevalent treatment approach for head and neck cancer. Nevertheless, high-dose radiation therapy can lead to numerous side effects, including xerostomia, dysgeusia, dysphagia, mucositis, radiation caries, fibrosis, limited mouth opening, and candidiasis. Surgical procedures performed in irradiated areas may also lead to complications such as infections, delayed healing, and dehiscence. One of the most serious complications associated with radiation therapy is osteoradionecrosis (ORN), which may manifest during or after the treatment process. Specific
References
- JR Antônio., et al. “Neurofibromatosis: chronological history and current issues”. Anais Brasileiros de Dermatologia 3 (2013): 329-343.
- Alves Júnior SF., et al. “Neurofibromatosis type 1: State-of-the-art review with emphasis on pulmonary involvement”. Respiratory Medicine 149 (2019): 9-15.
- Legius E., et al. “International Consensus Group on Neurofibromatosis Diagnostic Criteria (I-NF-DC); Huson SM, Evans DG, Plotkin SR. “Revised diagnostic criteria for neurofibromatosis type 1 and Legius syndrome: an international consensus recommendation”. Genetics in Medicine 8 (2021): 1506-1513.
- Carroll SL and Ratner N. “How does the Schwann cell lineage form tumors in NF1?” Glia 14 (2008): 1590-1605.
- Javed F., et al. “Oral manifestations in patients with neurofibromatosis type-1: a comprehensive literature review”. Critical Reviews in Oncology/Hematology 2 (2014): 123-129.
- Fahy E., et al. “Neurofibromatosis -1 diagnosed from an intraoral swelling - a case series”. Australian Dental Journal 2 (2021): 205-211.
- Bongiorno MR., et al. “Manifestations of the tongue in Neurofibromatosis type 1”. Oral Disease 2 (2006): 125-129.
- Go JH. “Benign peripheral nerve sheath tumor of the tongue”. Yonsei Medical Journal 5 (2002): 678-680.
- Buchholzer S., et al. “Type I Neurofibromatosis: Case Report and Review of the Literature Focused on Oral and Cutaneous Lesions”. Dermatopathology (Basel)1 (2021): 17-24.
- Maruyama M., et al. “Solitary neurofibroma of the floor of the mouth: a case report”. Case Reports in Otolaryngology 2011 (2011):
- Kubota S., et al. “Gingival Neurofibroma with Teardrop-Shaped Defects of the Interdental Alveolar Bone: An Unusual Oral Manifestation of Neurofibromatosis Type 1”. Journal of Craniofacial Surgery 3 (2019): e205-e207.
- Shetty B., et al. “Periodontal manifestations of von Recklinghausen neuro fibromatosis”. Journal of Indian Society of Periodontology 17 (2013): 253-256.
- Cunha KS., et al. “Neurofibromatosis typeI with periodontal manifestation. A case report and literature review”. British Dental Journal 196 (2004): 457-460.
- Hirbe AC and Gutmann DH. “Neurofibromatosis type 1: a multidisciplinary approach to care”. Lancet Neurology8 (2014): 834-843.
- Singhal MK., et al. “A Comparative Measurement of Edentulous Bone Between Cone Beam Computed Tomography vs. Dentascan CT in Implant Patients: In Vivo Study”. Journal of Pierre Fauchard Academy1 (2022): 9-15.
- Shapiro SD., et al. “Neurofibromatosis: Oral and radiographic manifestations”. Oral Medicine, Oral Surgery, Oral Pathology 58 (1984): 493-498.
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