Acta Scientific Dental Sciences (ASDS)(ISSN: 2581-4893)

Case Report Volume 6 Issue 10

A Grinspan Syndrome: A Case Report

Manisha Saxena*1, Sunil Nirankari2, Jaya Mathur3 and Shilpi Srivastava4

1Oral Medicine And Radiology, Rajasthan University of Health sciences, Jaipur, India
2PG scholar, OMR Derartment, Rajasthan Dental College, Jaipur, India
3PG scholar, Paciffic Dental College , Debari, Udaipur, India
4Mahatma Gandhi Dental College and Hospital, Sitapura, Jaipur, Rajasthan, India

*Corresponding Author: Manisha Saxena, Oral Medicine And Radiology, Rajasthan University of Health sciences, Jaipur, India.

Received: September 02, 2022; Published: September 22, 2022

Abstract

Oral lichen planus is common mucocutaneous condition involving skin, mucosa or both. Although exact etiology is unknown, an immune mediated pathogenesis is thought to be responsible for lichen planus. Oral lichen planus can occur with some systemic conditions also. Grinspan’s syndrome shows association between diabetes mellitus, hypertension and lichen planus. The causative factors are multifactorial such as OLR (oral lichenoid reaction) caused by drugs, exacerbation during stressful conditions, autoimmune mechanism, contact hypersensitivity and association of hepatitis C. The present case discuses about middle aged female with long history of diabetes mellitus and hypertension. Initially she had poor control of blood pressure and blood sugar which led to exacerbation of oral lichen planus. Oral prophylaxis to control local factors, proper monitoring of blood pressure and blood sugar, stress management, appropriate local application with corticosteroid definitely help her to keep it to lower level.

Keywords: Grinspan Syndrome; Oral Lichenoid Reaction; Diabetes Mellitus; Hypertension

References

  1. Vijay P., et al. “Oral Lichen Planus: A Case Report”. International Journal of Medical and Oral Research 3 (2016): 54-55.
  2. Soames JV and Southam JC. “Oral Pathology”. 3rd Oxford: Oxford University Press (1998): 151-156
  3. Greenberg MS and Glick M. “Burket’s Oral Medicine”. 10th Hamilton: BC Decker Inc (2003): 89-95.
  4. SG Fitzpatrick., et al. “The malignant transformation of oral lichen planus and oral lichenoid lesions: a systematic review”. Journal of the American Dental Association1 (2014): 45-56.
  5. Numan K¨Okten., et al. “Grinspan’s Syndrome: A Rare Case with Malignant Transformation”. Case Reports in Otolaryngology (2018): 4.
  6. F Tsushima., et al. “Malignant transformation of oral lichen planus: a retrospective study of 565 Japanese patients”. BMC Oral Health 21 (2021): 298.
  7. SB Ismail., et al. “Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation”. Journal of Oral Science (Nihon University School of Dentistry)2 (2021): 89-106.
  8. SM Hasan Aghbari., et al. “Malignant transformation of oral lichen planus and oral lichenoid lesions: A meta-analysis of 20095 patient data”. Oral Oncology 68 (2017): 92-102.
  9. Giuliani M., et al. “Rate of malignant transformation of oral lichen planus: A systematic review”. Oral Diseases 25.3 (2019): 693-709.
  10. MR Roopashree., et al. “Pathogenesis of oral lichen planus-a review”. Journal of Oral Pathology and Medicine 39 (2010): 729-734.
  11. Vincent SD., et al. “Oral lichen planus: The clinical, historical, and therapeutic features of 100 cases”. Oral Surgery, Oral Medicine, Oral Pathology 70 (1990): 165-171.
  12. Lo Muzio L., et al. “The treatment of oral aphthous ulceration or erosive lichen planus with topical clobetasol propionate in three preparations: A clinical and pilot study on 54 patients”. Journal of Oral Pathology and Medicine 30 (2001): 611-617.
  13. Eisen D., et al. “Oral lichen planus: Clinical features and management”. Oral Diseases 11 (2005): 338-349.
  14. Lavanya N., et al. “Oral lichen planus: An update on pathogenesis and Treatment”. Journal of Oral and Maxillofacial Pathology2 (2011).
  15. M Boorghani., et al. “Oral Lichen Planus: Clinical Features, Etiology, Treatment and Management; A Review of Literature”. JODDD1 (2010).

Citation

Citation: Manisha Saxena. “A Grinspan Syndrome: A Case Report”. Acta Scientific Dental Sciences 6.10 (2022): 67-70.

Copyright

Copyright: © 2022 Manisha Saxena. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.278

Indexed In





News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is April 30th, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue".
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US