A Mohamed Skkander*
Department of Chemistry, Velammal Engineering College, Chennai, India
*Corresponding Author: A Mohamed Skkander, Department of Chemistry, Velammal Engineering College, Chennai, India.
Received: May 4, 2022; Published: May 18, 2022
Isoflurane and Sevoflurane are inhalational anesthetics that belong to the halogenated ether group. They are used to induce and maintain general anesthesia. Isoflurane is currently approved for use in dogs, cats, horses, ornamental birds, reptiles, and small mammals such as rabbits in the United Kingdom, but sevoflurane is exclusively approved for use in dogs. Both have similar adverse effects, such as central nervous system depression, respiratory depression, myocardial depression, depression of body temperature regulating centers, hypotension, vasodilatation, and muscle relaxation. Both drugs can lower cerebral metabolic rate and produce vasodilatation leading to a rise in cerebral pressure. In patients with head trauma and/or cerebral pathology, this should be continuously monitored, and it may be required to ventilate them to keep carbon dioxide levels at an adequate level to prevent a further rise in cerebral pressure. When given equal amounts of sevoflurane and isoflurane, a group of dogs experienced less respiratory depression. In terms of total side effects, both are the same and therefore one agent is better than the other.
Keywords: Hypotension; Central Nervous System Depression; Respiratory Depression; Depression of Body Temperature; Muscle Relaxation; Cerebral Pressure
Citation: A Mohamed Skkander. “Appraisal of Isoflurane and Sevoflurane".Acta Scientific Biotechnology 3.3 (2022): 05-08.
Copyright: © 2022 A Mohamed Skkander. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.