Sanskar Rajput and Jyotsana Bidaliya*
Department of Microbiology and Biotechnology, School of Science, Gujarat University, Ahmedabad, Gujarat, India
*Corresponding Author: Sarita Sharma, Department of Microbiology and Biotechnology, School of Science, Gujarat University, Ahmedabad, Gujarat, India.
Received: January 24, 2022; Published: March 30, 2022
From past few years, the world is ravaged by a new pandemic whose magnitude of damage was never anticipated before. The pandemic, caused by a virus was first reported in Wuhan city of China. It was initially thought to be seasonal disease but was later declared a pandemic due to the damage caused worldwide. The disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was christened as Coronavirus Disease 2019 COVID-19 by World Health Organisation (WHO). Coronaviruses are common in bats but can infect humans too. It hijacks the replication machinery of the human cells by attaching itself to the special receptors present on the cell surfaces like ACE-2 to gain entry into cell. It then proceeds to replicate its genetic material and ultimately increase the viral count inside the body. COVID-19 has pneumonia like symptoms. Some possible symptoms experienced are high fever, severe cough, body pain, loss of taste (ageusia) or smell capacity, sore throat. In some cases diarrhoea, skin rashes, or fingers discolouration, eyes pain or irritation, shortening in breath and acute chest pain. Scientists all around the world are engaged in devising strategies and methods to tackle the pandemic. Some possible strategies that can be or were or are employed are discussed in this review article.
Keywords: SARS-CoV-2; COVID-19 Vaccines; Drugs and Convalescent Plasma; ACE-2 Receptor; Mpro; RdRp
Citation: Sanskar Rajput and Jyotsana Bidaliya. “Our Current Understanding of SARS-CoV-2 and Strategies for Management of COVID- 19; A Comprehensive Review".Acta Scientific Biotechnology 3.2 (2022): 12-24.
Copyright: © 2022 Sanskar Rajput and Jyotsana Bidaliya. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.