Acta Scientific Agriculture (ASAG)(ISSN: 2581-365X)

Review Article Volume 4 Issue 2

Dietary Polysaccharides from Allium Species: A Critical Review in Dietary Polysaccharides from Allium Species: Extraction, Characterization, Bioactivity, And Potential Utilization

Dery Bede1,2* and Lou Zaixiang1,2

1State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, PR China
2National Engineering Research Center for Functional Food, Jiangnan University, China

*Corresponding Author: Dery Bede, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, PR China.

Received: January 17, 2020; Published: January 24, 2020



  Allium species are broadly used as a functional food and nutraceutical products because of its recognized nutritive and medicinal properties. It has been used since antiquity in Asia as a traditional medicine for the management and treatment of conditions such as diabetes, hypertension, cancer, inflammation, gastrointestinal problems as well as microbial infestations. There have been studies over the past decade on the extraction of the bioactive compounds from various Allium species and both in vivo and in vitro experiments suggest that Allium species can be used as an alternative in preventing and managing diseases stated in this paper. This review summarizes the recent developments of Allium species polysaccharides, including their production, extraction and isolation methods, chemical structures, biological and pharmacological properties and mechanism of actions.

Keywords: Allium Species; Polysaccharides; Extraction Methods; Cardiovascular Disease



  1. Abbas H M K., et al. “Antimicrobial Potential of Genes from Garlic (Allium sativum L.)”. In Studies on Garlic. IntechOpen (2019).
  2. Ajayi GO., et al. “Hepatoprotective and some haematological effects of Allium sativum and vitamin C in lead-exposed wistar rats”. International Journal of Medicine and Medical Sciences 1.3 (2009): 64-67.
  3. Al-Snafi AE. “Antiparasitic effects of medicinal plants (part 1)-A review”. IOSR Journal of Pharmacy 6.10 (2016): 51-66.
  4. Alonso-Salces RM., et al. “Pressurized liquid extraction for the determination of polyphenols in apple”. Journal of Chromatography A 933 (2001): 37-43.
  5. Anthony JP., et al. “Plant active components-a resource for antiparasitic agents?” Trends in Parasitology 21.10 (2005): 462-468.
  6. Apolinário AC., et al. “Inulin-type fructans: A review on different aspects of biochemical and pharmaceutical technology”. Carbohydrate Polymers 101 (2014): 368-378.
  7. Archer JC and Jenkins Jr RG. “Automated milk fat extraction for the analyses of persistent organic pollutants”. Journal of Chromatography B 1041 (2017): 70-76.
  8. Astaneh R K., et al. “The effects of selenium on some physiological traits and K, Na concentration of garlic (Allium sativum L.) under NaCl stress”. Information Processing in Agriculture 5.1 (2018): 156-161.
  9. Azwanida NN. “A review on the extraction methods use in medicinal plants, principle, strength and limitation”. Medicinal and Aromatic Plants 4.196 (2015): 412-2167.
  10. Barazani O., et al. “Cadmium accumulation in Allium schoenoprasum L. grown in an aqueous medium”. Chemosphere 57.9 (2004): 1213-1218.
  11. Batchu S N., et al. “Bioactive Compounds in Heart Disease”. Bioactive Food as Dietary Interventions for Cardiovascular Disease: Bioactive Foods in Chronic Disease States 431 (2012).
  12. Baumgartner S., et al. “Characterisation of the high-molecular weight fructan isolated from garlic (Allium sativum L.)”. Carbohydrate Research 328.2 (2000): 177-183.
  13. Benítez V., et al. “Onion (Allium cepa L.) by-products as source of dietary fiber: physicochemical properties and effect on serum lipid levels in high-fat fed rats”. European Food Research and Technology 234.4 (2012): 617-625.
  14. Beusterien K., et al. “Use of conjoint analysis to assess breast cancer patient preferences for chemotherapy side effects”. The Oncologist 19.2 (2014): 127-134.
  15. Block E., et al. “Allium chemistry: HPLC analysis of thiosulfinates from onion, garlic, wild garlic (ramsoms): leek, scallion, shallot, elephant (great-headed) garlic, chive, and Chinese chive. Uniquely high allyl to methyl ratios in some garlic samples”. Journal of Agricultural and Food Chemistry 40 (1992): 2418-2430.
  16. Boulila A., et al. “Enzyme-assisted extraction of bioactive compounds from bay leaves (Laurus nobilis L.)”. Industrial Crops and Products 74 (2015): 485-493.
  17. Bray F., et al. “Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries”. CA: A Cancer Journal for Clinicians 68.6 (2018): 394-424.
  18. Capasso A. “Antioxidant action and therapeutic efficacy of Allium sativum L”. Molecules 18.1 (2013): 690-700.
  19. Carr A G., et al. “A review of subcritical water as a solvent and its utilisation for the processing of hydrophobic organic compounds”. Chemical Engineering Journal 172 (2011): 1-17.
  20. Chandrashekar PM., et al. “Isolation, structural elucidation and immunomodulatory activity of fructans from aged garlic extract”. Phytochemistry 72 (2011): 255-264.
  21. Chandrashekara PM and Venkatesh YP. “Immunostimulatory properties of fructans derived from raw garlic (Allium sativum L.)”. Bioactive Carbohydrates and Dietary Fibre 8 (2016): 65-70.
  22. Charlotta Turner. “Modern Extraction Techniques Food and Agricultural Samples. American Chemical Society”. Division of Agricultural and Food Chemistry (1970).
  23. Chemat F., et al. “Ultrasound assisted extraction of food and natural products. Mechanisms, techniques, combinations, protocols and applications. A review”. Ultrasonics Sonochemistry 34 (2017): 540-560.
  24. Chen HF., et al. “Two new steroidal saponins from Allium macrostemon Bunge and their cytotoxity on different cancer cell lines”. Molecules 14 (2009): 2246-2253.
  25. Chen J and Huang G. “Antioxidant activities of garlic polysaccharide and its phosphorylated derivative”. International Journal of Biological Macromolecules 125 (2019): 432-435.
  26. Cheng H and Huang G. “Extraction, characterisation and antioxidant activity of Allium sativum polysaccharide”. International Journal of Biological Macromolecules 114 (2018): 415-419.
  27. Chope GA., et al. “Alliums (Onion, Garlic, Leek and Shallot)”. Health-Promoting Properties of Fruits and Vegetables (2011): 5-28.
  28. Csiszar J., et al. “Antioxidant enzyme activities in Allium species and their cultivars under water stress”. Plant Soil and Environment 53.12 (2007): 517.
  29. Cui SW. “Food carbohydrates: chemistry, physical properties, and applications”. CRC press (2005).
  30. de Camargo AC., et al. “Enzyme-assisted extraction of phenolics from winemaking by-products: Antioxidant potential and inhibition of alpha-glucosidase and lipase activities”. Food Chemistry 212 (2016): 395-402.
  31. De Castro MDL and Garcıa-Ayuso LE. “Soxhlet extraction of solid materials: an outdated technique with a promising innovative future”. Analytica Chimica Acta 369 (1998): 1-10.
  32. De Castro MDL and Priego-Capote F. “Soxhlet extraction: Past and present panacea”. Journal of Chromatography A 1217.16 (2010): 2383-2389.
  33. Diriba-Shiferaw G., et al. “Bulb quality of Garlic (Allium sativum L.) as influenced by the application of inorganic fertilizers”. African Journal of Agricultural Research 8 (2013): 5387-5398.
  34. Djurdjevic L., et al. “Allelopathic potential of Allium ursinum L”. Biochemical Systematics and Ecology 32.6 (2004): 533-544.
  35. Dominguez H and Munoz MJG. Water Extraction of Bioactive Compounds: From Plants to Drug Development. Elsevier (2017).
  36. Dorhoi A., et al. “Modulatory effects of several herbal extracts on avian peripheral blood cell immune responses”. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives 20.5 (2006): 352-358.
  37. Dziri S., et al. “Phenolic constituents, antioxidant and antimicrobial activities of rosy garlic (Allium roseum var. odoratissimum)”. Journal of Functional Foods 4.2 (2012): 423-432.
  38. Ebringerova A and Heinze T. “Xylan and xylan derivatives-biopolymers with valuable properties, 1. Naturally occurring xylans structures, isolation procedures and properties”. Macromolecular Rapid Communications 21.9 (2000): 542-556.
  39. Eksi G., et al. “Fortification of Functional and Medicinal Beverages With Botanical Products and Their Analysis”. In Engineering Tools in the Beverage Industry (2019): 351-404.
  40. Emami S., et al. “The effect of garlic intake on glycemic control in humans: a systematic review and meta-analysis”. Progress in Nutrition 19 (2017): 10-18.
  41. Eskilsson CS and Björklund E. “Analytical-scale microwave-assisted extraction”. Journal of Chromatography A 902.1 (2000): 227-250.
  42. Foster BC., et al. “An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic”. Journal of Pharmacy and Pharmaceutical Sciences 4 (2001): 176-184.
  43. Gao Z., et al. “Optimization of selenylation modification for garlic polysaccharide based on immune-enhancing activity”. Carbohydrate Polymers 136 (2016): 560-569.
  44. Golovchenko VV., et al. “Structure of pectic polysaccharides isolated from onion Allium cepa L. using a simulated gastric medium and their effect on intestinal absorption”. Food Chemistry 134.2 (2012): 1813-1822.
  45. Gonçalves CB., et al. “Partition of nutraceutical compounds in deacidification of palm oil by solvent extraction”. Journal of Food Engineering 81.1 (2007): 21-26.
  46. Goncharov N., et al. “Organosulfur compounds as nutraceuticals”. In Nutraceuticals (2016): 555-568.
  47. Goren A., et al. “Antiviral composition derived from allium CEPA and therapeutic use thereof”. Google Patents (2002).
  48. Griffiths G., et al. “Onions—a global benefit to health”. Phytotherapy Research 16.7 (2002): 603-615.
  49. Grimmer G. “Environmental carcinogens: polycyclic aromatic hydrocarbons”. Crc Press (2018).
  50. Han SB., et al. “The inhibitory effect of polysaccharides isolated from Phellinus linteus on tumor growth and metastasis”. Immunopharmacology 41.2 (1999): 157-164.


Citation: Dery Bede and Lou Zaixiang. “Dietary Polysaccharides from Allium Species: A Critical Review in Dietary Polysaccharides from Allium Species: Extraction, Characterization, Bioactivity, And Potential Utilization" . Acta Scientific Agriculture 4.2 (2020): 98-112.


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