Dr Jinwei Zhang is a Principal Investigator at the University of Exeter Medical School, UK. His laboratory studies signalling pathways that associated with human diseases, for examples, neuropsychiatric disorders, such as epilepsy and autism (WNK-SPAK-KCC2) and nephrology and hypertension (CUL3/KLHL3-WNK-SPAK-NCC) and concern with elucidating and targeting ion transporters, kinases, protein-protein interactions using genetic mouse models, small molecules and CRISPR/Cas9 knock-in and knock-out technologies to aid discovery and validation of new potential drug targets. He has published more than 50 articles in journals including Nature Medicine, Cell Metabolism, Neuron, Nature Communications, EMBO molecular medicine, Science Signalling, Human Molecular Genetics etc. and has achieved more than 1800 citations, H-index=22.
WNK-SPAK kianse signalling, N(K)CCs and KCCs, Cellular Chloride Volume Regulation, Epilepsy, Hypertension