Acta Scientific Nutritional Health (ISSN: 2582-1423)

Perspective Volume 4 Issue 1

MicroRNA Opens up a New World for Nutrition Research

Shaw Watanabe*

President, Asia Pacific Clinical Nutrition Society, Japan

*Corresponding Author: Shaw Watanabe, President, Asia Pacific Clinical Nutrition Society, China.

Received: November 21, 2019; Published: December 05, 2019


  Several landmark discoveries have deepened our understand-ing of living organisms, for example the structure of the cell, the role of organelles, and the mechanisms of protein synthesis. Re-cent food and health metabolomic research has gone one step beyond classical nutrient-based concepts of nutrition, approach-ing the essence of biology. So far, we have delved into the cause of diseases at the genome and epigenome level. A further step is the discovery of microRNAs (miRNA), and their importance in control-ling health and diseases [1-4]. We are thus closer to understanding the mysteries of life.

  "Small-interfering RNA” were discovered in nematodes in 1993 [1]. Small RNA molecules are made of single-stranded mRNA, and their sequences are complementary to specific mRNA, to which they bind for silencing gene expression. On the other hand, miRNA have partially complementary sequences. They bind to a number of mRNA sequences, and suppress the expression of various genes by physically inhibiting the translation of their mRNA [2-4]. The initial description of miRNA appeared in a paper published in Sci-ence in 2001, and research has been progressing rapidly since then. New types of miRNA are being discovered every year. It ap-pears that miRNAs exist in various types of plants and animals, regardless of species [5-8]. So far, in humans, 2656 miRNAs have been identified with a precise length of 22 bases.



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Citation: Shaw Watanabe. "MicroRNA Opens up a New World for Nutrition Research".Acta Scientific Nutritional Health 4.1 (2020): 38-39.

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