Assistant Professor of Animal Genetics and Breeding, West Bengal University of Animal and Fishery Sciences, Kolkata, India
*Corresponding Author: Aruna Pal, Assistant Professor of Animal Genetics and Breeding, West Bengal University of Animal and Fishery Sciences, Kolkata, India.
Received: June 19, 2018; Published: August 21, 2018
Citation: Aruna Pal. “Nutrigenomics- An Emerging Area". Acta Scientific Nutritional Health 2.9 (2018).
Nutrigenomics is an emerging issue that combines a certain area of nutrition and molecular tools to study the level of responses of different nutrients in the body of a population. It is a field of research related to the analysis and understanding of the molecular level of interactions between dietary bioactive components with gene expressions at different levels. The actual uptake of nutrition we receive from food or exogenous source depends on the genetics. The uptake, absorption and assimilation of neutraceuticals, which prevents diseases is directly regulated by nutrigenomics through gene-diet interaction or epigenetics. The onset of various diseases (as diabetes, cardiovascular diseases, osteoporosis, ageing, cancer, immunological diseases and neurological disorders) directly depends on the nutrient imbalances, but the susceptibility varies from individual to individual with the similar kind of nutrition level, which is entirely due to nutrigenomics. The study is equally applicable for human and animals. To study the efficacy of newer probiotics or vitamins or minerals as neutraceuticals in basic biological processes, as growth, reproduction or immunity, nutrigenomics can be very well studied with Real-time PCR or DNA microarray. Differential mRNA expression profile of genes involved with various level of nutrients supplementation as probiotics or micronutrients provides us the most useful information for determination of efficacy and appropriate dosage of probiotics or micronutrient and prevention of toxicity induced by excess administration. Such studies are in progress in our laboratory
Copyright: © 2018 Aruna Pal. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.