Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Case Report Volume 7 Issue 9

Beta Thalassemia Major and Chronic Myeloid Leukemia in a Young Adult Male: A Rare Combination

Sai Aditya G1, Gurpreet Kaur2*, Ankur Ahuja3, Venkatesan Somasundaram4 and Yanamandra Uday5

1Resident, Department of Pathology, Armed Forces Medical College, Pune, India
2Associate Professor, Department of Pathology, Armed Forces Medical College, Pune, India
3Professor, Department of Pathology, Armed Forces Medical College, Pune, India
4Professor and Head of the Department, Department of Pathology, Armed Forces Medical College, Pune, India
5Professor Department of Medicine, Armed Forces Medical College, Pune, India

*Corresponding Author: Gurpreet Kaur, Associate Professor, Department of Pathology, Armed Forces Medical College, Pune, India.

Received: April 15, 2024; Published: August 31, 2024

Abstract

Beta-thalassemia major (β-TM) is a severe hereditary haemoglobinopathy that is rarely associated with hematological malignancies.Though isolated case reports of association with acute lymphoblastic leukemia, acute myeloid leukemia is known. Only a few case reports of the association of β-TM and chronic myeloid leukemia (CML) are known. We present a case of a 25-year-old male with β-TM who later developed CML. The patient's management involved a multidisciplinary approach, incorporating hematological, molecular, and genetic assessments. This report indicates that malignancies should be suspected and kept in mind in patients with β-thalassemia syndromes presenting with proposed signs and symptoms including unexplained lymphadenopathy, leukocytosis, and splenomegaly. This case highlights the importance of comprehensive evaluation and tailored therapeutic strategies in complex hematological disorders.

 Keywords: Chronic Myeloid Leukemia; Beta Thalassemia; Adult Male; Rare Combination

References

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Citation

Citation: Gurpreet Kaur., et al. “Beta Thalassemia Major and Chronic Myeloid Leukemia in a Young Adult Male: A Rare Combination”. Acta Scientific Neurology 7.9 (2024): 23-26.

Copyright

Copyright: © 2024 Gurpreet Kaur., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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